The most popular oral drug class for erectile dysfunction is phosphodiesterase type 5 (PDE5) inhibitors, such as Viagra and Cialis. Only one other class of oral medicines for erectile dysfunction has FDA clearance (ED). Cenforce 200 and Malegra 100 are used to treat erectile dysfunction in men, which is defined as the inability to successfully produce or maintain a penile big erection in order to perform sexual acts.

Cyclic guanosine monophosphate is prevented from deteriorating by inhibitors of phosphodiesterase type 5. (cGMP). In reaction to sexual stimulation, the substance aids in the retention of blood in the penile tissue, facilitating an erection. The penile region's blood vessel dilatation and circulation are also improved by blocking PDE5.

Additionally, when taken with nitrates and alpha-blockers, PDE5 inhibitors may result in hypotension since they lower vascular pressure (Trusted Source).