It's essential to be aware of certain model years that have been associated with potential issues or concerns. While the Acura MDX has generally been well-received for its performance, luxury features, and reliability, some years have stood out for various reasons. The first-generation models, produced between 2001 and 2006, may be more prone to transmission problems, particularly in earlier years. Additionally, some owners have reported issues with the power steering system in the 2003 model. In the second generation (2007-2013), the 2007 and 2010 models have been noted for transmission issues and battery problems, respectively. It's worth noting that Acura has addressed many of these concerns in subsequent models. As with any used vehicle purchase, thorough research, vehicle history checks, and pre-purchase inspections are crucial to ensuring a reliable and trouble-free driving experience.